Contrave®
Background
Contrave (bupropion SR/naltrexone SR) is an investigational medication for the treatment of obesity.
With its unique mechanism of action in the CNS, Contrave has the potential to change the way obesity is treated by:
- Initiating weight loss by reducing appetite and increasing metabolism
- Allowing the body to sustain continued weight loss by offsetting its natural tendency to fight back and slowing down the weight loss process
- Addressing the reward system in the brain that causes food cravings
Contrave is a combination of two well-established drugs, bupropion and naltrexone, in a sustained release formulation (SR).
- The active ingredients of Contrave have been used for over 20 years.
- Bupropion is a widely-prescribed antidepressant and smoking cessation medication; naltrexone is a treatment for alcohol and opioid addiction.
- We believe that bupropion helps initiate weight loss while naltrexone may sustain weight loss by preventing the body’s natural tendency to counteract efforts to lose weight.